Effects of comorbid substance use and personality disorders on risk for violence in schizophrenia

Abstract

Clozapine remains the most effective treatment of aggressive behavior in schizophrenia. However, in cases of persistent aggression it needs to be supplemented by psychosocial approaches.

Treatment of substance use comorbidity must be an integral part of therapy. Novel long-term treatments of persistent aggression are based on cognitive skills and behavioral reward structure as well as anger management.

Keywords

• schizophrenia
• aggression
• violence
• psychopathy
• antisocial personality disorder
• substance use disorder