Abstract
Author describes hormonal treatment of breast cancer pacients and review gynaecological care from prevention and diagnostics to monitoring of the first line hormonal treatment. Reasons of increasing breast cancer incidence are discussed and historical overview of hormonal treatment posibilities in pacients with breast cancer is summarized.
The main part of the article characterizes influence of tamoxifen into woman organism, especially in her genital tract (endometrium changes) and side effects are analysed. The retrospective trial (Dept.
Obst. and Gyn. 3-rd Medical Faculty) focusing pathological changes of endometrium under tamoxifen influence is mentioned. Design of monitoring algorithm of breast cancer patients with intact uterus under treatment of tamoxifen is elaborated.
Complications and difficulties of this monitoring are specified. Another problem, controversial hormonal replacement therapy in breast cancer patients suffered from climacteric syndrom is solved.