Several pieces of evidence suggest the involvement of a wide spectrum of tyrosine, serine/threonine and lipid phosphatases in Parkinson's disease. Here we review the currently available data.
However, experimental evidence is still very limited and the genome-wide sequencing or proteomic analyses of dorsal motor nuclei and of the olfactory bulbs and nuclei may identify more phosphatases involved in the pathophysiology of Parkinson's disease.