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New selective inhibitors of CYP2B4 and an activator of CYP3A6 in rabbit microsomes

Publication at First Faculty of Medicine, Faculty of Mathematics and Physics |
2000

Abstract

New selective inhibitors of CYP2B subfamily enzymes (2-isopropenyl-2-methyladamantane and 3-isopropenyl-3-methyldiamantane) were discovered. These inhibitors act as competitive inhibitors with respect to the enzyme substrate.