Nucleophilic Reactivity of Perhydro-3,6,9,12-tetraazacyclopenteno[1,3-f,g]acenaphthylene. A Unified Aproach to N-Monosubstituted and N,N''-Disubstituted Cyclene Derivatives

Abstract

Perhydro-3,6,9,12-tetraazacyclopenteno[1,3-f,g] is readily mono- and dialkylated on nitrogen with alkyl bromides and iodides giving mono- and bis-quarternary ammonium salts. The title compound is a unified starting material for the preparation of cyclene based chelators.

Keywords

• complexes
• cyclene derivatives
• acenaphthene derivative