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Human cytochromes P450 1A1/2 and NADPH:cytochrom P450 reductase activate carcinogenic aristolochic acid to form DNA adducts found in patients with Chinese herbs nephropathy

Publication at First Faculty of Medicine, Faculty of Mathematics and Physics |
2003

Abstract

Carcinogenic aristlochic acid causing the Chinese herbs nephropathy and carcinogenic processes is activated by microsomal cytcorhoems P450 1A1 and 1A2