Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome P450 reductase

Publikace na 1. lékařská fakulta, Matematicko-fyzikální fakulta |

2003

Abstrakt

A strong mutagen and air pollutant 3-nitrobenzanthrone is metaboliyed by human NADPH:cytochrome P450 reductase and human recombinant cytochromes P450 to species binding covalently to DNA

Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome P450 reductase

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