Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome P450 reductase
2003
Abstract
A strong mutagen and air pollutant 3-nitrobenzanthrone is metaboliyed by human NADPH:cytochrome P450 reductase and human recombinant cytochromes P450 to species binding covalently to DNA