32P-Postlabelling analysis of DNA adducts with 1-(phenylazo)-2-naphthol (Sudan I, Solvent Yellow 14) formed in vivo in Fisher 344 rats

Abstrakt

The DNA adduct formed from carcinogenic azo dye Sudan I were detected of DNA of urinary bladder of rats exposed to this azo dye, Two of these adducts are the same as those formed from Sudan I or its 6-OH derivate after activation.