Publication at First Faculty of Medicine, Third Faculty of Medicine |
1996
Abstract
Sleep disturbances are characteristic symptoms of affective disordes. Either insomnia or hypersomnia are frequent phenomena occurring within the initial phases of illness.
The sleep process is under the circadian control (Borbely, 1982), and the pathological state can be interpreted as a result of changes in amplitude, phase or period of the circadian rhythm. Both phase-advanced and phase-delayed mechanisms were described in different types of depressions