The primary objective was to compare the clinical, radiologic, laboratory and scintigraphic features in 28 patients with erosive osteoarthritis and in 24 with nonerosive hand osteoarthritis.Other objectives were to evaluate clinical, radiographic and scintigraphic progression in the two groups over a two-year period and estimate the value of bone scintigraphy for predicting clinical and radiographic progression.These results suggest that bone scintigraphy may be useful for predicting clinical and radiographic progression of hand osteoarthritis with or without erosions.