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High-performance liquid-chromatographic determination of 5-aminosalicylic acid and its metabolites in blood plasma

Publication at Central Library of Charles University, Faculty of Pharmacy in Hradec Králové |
2006

Abstract

HPLC determination of 5-aminosalicylic acid and its metabolites after the precipitation of blood plasma, a lipophilicity increasing derivatization, liquid-liquid extraction followed by HPLC with UV-PDA, fluorescence and MS detection and use of two IS