Targeted synthesis of 1-(4-hydroxyiminomethylpyridinium)-3-pyridiniumpropane dibromide - a new nerve agent reactivator

Abstrakt

Preparation of a new AChE reactivator which has no substituent on the second pyridinium ring is described; a potent oxime for treatment of tabun and cyclosarin-caused intoxications was thus obtained via slight modification of the reactivator structure (compared to trimedoxime and K027)