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Tetrazoles: LI. Synthesis of 5-substituted tetrazoles under microwave activation

Publication at Faculty of Pharmacy in Hradec Králové |
2007

Abstract

Reaction of nitriles with sodium azide in the presence of ZnCl2 under microwave activation (MWA) leads to the formation of 5-substituted tetrazoles in high yields; therewith the process is 2-3 times shorter than the inactivated reaction