HLA-identical umbilical cord blood transplantation from a sibling donor in juvenile myelomonocytic leukemia

Abstract

In this report we describe 5 JMML patients registered in the database of the European Working Group on Childhood MDS (EWOG-MDS), who have received umbilical cord stem cells from an HLA-identical sibling. We conclude that in JMML umbilical cord stem cellscan be considered a good alternative source for HSCT.However, whether the use of sibling HLA-identical UCBshould be advocated needs to be confirmed in largerseries of JMML patients.

Keywords

• stem-cell transplantation
• bone-marrow-transplantation
• working-group
• children
• jmml