Subpial astrocytosis and focal leptomeningeal angiotropic astrocytosis leading to vascular compression: observations made in a case of mitochondrial encephalopathy

Abstract

We performed standard histological, immunohistochemical, and ultrastructural examinations of formalin fixed samples of the brain (frontal cortex, brain stem, basal ganglia, and spinal medulla) of a male patient, aged 12, who succumbed to a mitochondrial disorder, characterized as MERRF (8344A > G).

Keywords

• Subpial astrocytosis
• focal leptomeningeal angiotropic astrocytosis
• vascular compression