A rise of troponins reflects irreversible myocardial cell necrosis. Accordingly, abnormal values have been described in various conditions not related to acute coronary disease, such as myocarditis, pulmonary embolism, acute heart failure, septic shock, as a result of cardiotoxic drugs and following therapeutic procedures such as electrophysiological ablations, or electrical cardioversion.
This review focuses on the incidence and clinical significance of increased troponin in conditions with symptoms that resemble acute myocardial infarction.