Diagnosis of non-Aspergillus mould infections remains challenging despite application of a wide spectrum of non-culture-based microbiological techniques. Invasive diagnostic procedures are often essential.
Here we present the case of 4 years old girl diagnosed with Coprinellus domesticus (anamorph Hormographiella verticillata) pneumonia during induction chemotherapy for acute lymphoblastic leukaemia. She was effectively treated with amphotericin B lipid complex during ongoing intensive chemotherapy and subsequently underwent allogeneic hematopoietic stem cell transplantation from unrelated donor.
Voriconazole was used as long term secondary prophylaxis.