Abstract
The rise of antibiotic resistance in bacteria worldwide inactivates the current effect of these essential drugs. The main cause is excessive consumption of antibiotics.
A similar situation as in the United States of America appeared in the Czech Republic. Prior to 1990, restrictions on certain antibiotics were applied to a greater extent in the Czech Republic, the release of which in an effort to ensure targeted treatment was subject to consultation with an employee of the Antibiotic Center.
Regardless of the fact that the real reason for the restriction of antibiotics at that time was probably economic, the Czech Republic belonged to the countries with a relatively low incidence of resistance in the main causes of bacterial infectious diseases until the first half of the 1990s. Until 1993, the average annual consumption of antibiotics was approximately 15 DDD / 1,000 / d (defined daily doses per 1,000 inhabitants per day).
In 1993, the total consumption of antibiotics in the Czech Republic increased sharply due to non-compliance with the principles of antibiotic policy by attending physicians and for the next six years remained permanently at a level almost one quarter higher compared to the previous period of 21 DDD / 1,000 / day. The increase in consumption was most pronounced in the group of new macrolides, ω-aminopenicillins and fluorinated quinolones.
This situation led to a similar decision, as stated by the author of the article, to prepare material - a guideline for the correct prescription of antibiotics in respiratory infections. Based on the request of professional societies of general practitioners and general practitioners for children and adolescents, a working group of microbiologists and infectionists prepared material, which was further opposed by pneumologists, otorhinolaryngologists and pediatricians and then consensually submitted to the Czech Medical Society and published in the General Practitioner and other professional journals. ; also on the website www.cls.cz.
No one in the pharmaceutical industry was involved in the development of the guidelines.