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Growth in Very Young Children Undergoing Chronic Peritoneal Dialysis

Publikace na 2. lékařská fakulta |
2011

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Abstrakt

Very young children with chronic kidney disease often have difficulty maintaining adequate nutrition and having high prevalence of short stature. Data from 153 children in 18 countries who commenced chronic peritoneal dialysis at <24 months of age were analyzed.

North American and European centers accounted for nearly all feeding by gastrostomy. 26% of North American children were obese and 50% of Turkish children were malnourished (P < 0.005). Body length decreased sharply during the first 6 to 12 months of life and then tended to stabilize.

Time fed by gastrostomy significantly associated with higher lengths over time (P < 0.001).The use of biocompatible peritoneal dialysate and administration of growth hormone independently associated with improved length.In summary, growth and nutritional status vary regionally in very young children treated with chronic peritoneal dialysis. Summary: the use of gastrostomy feeding, biocompatible dialysis fluid, and growth hormone therapy associate with improved linear growth.