Abstract
We thank Höckel and Horn for their very important comments. First, it is true that premature infants have an increased risk of morbidity with low birth weight and before 28 weeks of pregnancy.
Perhaps this risk would be better categorised by birthweight (eg, by use of the official perinatology classification: 500-1000 g, 1000-1500 g, 1500-2000 g, and >2000 g). However, in our Review,1 we were only able to find detailed division of premature delivery in two papers.
In future, we encourage publication of common oncological and pregnancy outcomes and for uniform classification to be used. Second, it would be interesting to know the oncological outcomes in patients in whom the fertility-preserving surgery was cancelled, but this information is not available in published works. 9,5% of vaginal radical trachelectomies were cancelled (4,5% for patients with positive lymph nodes), and 16,0% of abdominal radical trachelectomies were cancelled (15,0% for patients with positive lymph nodes).
Morbidity and mortality of these women are not reported in most papers. We agree that it is pity these data and outcomes were not reported, but the number of patients are too small and the types of treatment are so different (eg, radical surgery, primary chemoradiotherapy) that the results will not predict anything of benefit to future practice.