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The efficiency of colonic capsule endoscopy in detection of colorectal polyps and cancers compared to colonoscopy - multicenter, prospective, cross-over study

Publication at First Faculty of Medicine, Faculty of Medicine in Hradec Králové |
2014

Abstract

The national colorectal cancer screening program has been running in the Czech Republic (CR) since 2000. It is based on an examination by faecal occult blood test (FOBT) and colonoscopy.

In 2012 the target population coverage reached the level of 25.8%. The European guidelines set the acceptable participation rate to at least 45%, and the recommended aim is 65%.

For this reason, other screening modalities are examined. Capsule colonoscopy is one of these possible methods.

In CR,a multicentre study has been running since 2011. Its interim analysis is presented here.

The main aim of the study was to assess the accuracy of second-generation capsule colonoscopy (CCE2) in detection of colorectal neoplasia (polyps, adenomas, cancers) in comparison to colonoscopy (OC). The secondary aims were: comparison of colon cleansing, number of complications and target population acceptance of both methods (CCE2 and OC).