Abstract
Chronic urticaria therapy and management are challenging. The actualized EAACI/ GA(2)LEN/EDF/WAO guidelines provide the physicians with evidence based guide in diagnostics and therapy.
Structured history is the most beneficial diagnostic tool to identify the type of chronic urticaria. Non sedative H1 antihistamines represent the drugs of first chice, even in supratherapeutic doses.
In third sted immunosupressants are added. Individual cases need an individual approach, including the use of less ordinary empirical drugs.
Relevant education and psychosomatic approach are for management of chronic urticaria also important.