Publication
Abstract
Background: Local application of adipose-derived mesenchymal stem cells (ADSCs) is considered as a promising method for the treatment of perianal fistula in patients with Crohn's disease. More clinical and experimental studies are needed to evaluate this technique.
In vivo bioluminescence imaging using firefly luciferase can clarify the distribution and viability of the cells after implantation. The aim of the study was to evaluate the fistula healing after application of ADSCs in perifistular tissue.