Pyogenic granuloma in the documentation of the Department of Dentistry, Charles University, Faculty of Medicine and University Hospital, Hradec Králové
Abstract
Causes of the pyogenic granuloma are not precisely known yet. We can only assume stimuli that support local endothelial cell proliferation and angiogenesis.
Known factors are chronic local irritation and trauma, hormonal changes and effects of some drugs. Pyogenic granuloma can occur at any age but it is more common in children and young adults.
Clinically appears as an exophytically, fast growing, broad sessile tumor, which bleeds easily after irritation. It was observed in colors from red (younger lesions, more capillaries) to pale pink (older lesions, more connective tissue).
Microscopically is characterized as a lobular capillary hemangioma. In differential diagnosis we consider both benign and malignant mucosal lesions.
The treatment is always surgical. Complete excision is important, followed by histopathological examination and patient's education.
At the Department of Dentistry, Faculty Hospital in Hradec Kralove, was diagnosed and treated a total of 24 patients with pyogenic granulomas of the oral mucosa (12 men, 12 women) aged 5-82 years in the period 2009 - 2013. Recurrence was observed in 3 patients, always within 2 months after primary excision.