Tapentadol in chronic nonmalignant pain - a new effective analgesic for the treatment of diabetic neuropathy?
Abstract
Tapentadol is a new, centrally acting analgesic with a dual mechanism of action, which is an agonist at μ opioid receptors and also inhibits the reuptake of norepinephrine. The basis of this article is notification of a new option for treatment with tapentadol in chronic non-cancer pain for patients with diabetic poly- neuropathy, reminders are common indications such as pain especially in the joints or back pain.
Commonly used drug with a dual mechanism of is tramadol, but when comparing drugs tapentadol has a faster onset of action, improved and optimized profile of adverse reactions and also a smaller risk of drug interactions. Case reports are a practical guide to the use and setting of treatment with tapentadol especially in diabetic polyneuropathy.