Oral penicillin-associated acute kidney injury in an infant with acute pyelonephritis

Abstrakt

Beta-lactam-associated acute tubulointerstitial nephritis (ATIN) is a rare condition in childhood. We report the case of an infant with penicillin-associated ATIN and concomitant acute pyelonephritis resulting in the development of severe acute kidney injury (AKI).

The treatment consisted of penicillin suspension and appropriate AKI management, which required a short period of dialysis. Finally, full recovery and normalization of laboratory parameters occurred.

We present here the first case of oral penicillin-associated ATIN in childhood.

Klíčová slova

• acute kidney injury
• acute tubulointerstitial nephritis
• penicillin