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Trimetazidine in clinical practice

Publication at First Faculty of Medicine |
2015

Abstract

Trimetazidine is an anti-anginal drug included in the group of so-called metabolic modulators. The mechanism of its anti-anginal and anti-ischaemic effects is inhibition of beta-oxidationof fatty acids and energy transfer in the form of ATP molecules to glucose oxidation which is a more effective method of energy production in ischaemic myocardium in term of oxygen consumption.