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The prevalence of human papillomavirus in patients with oral lichen planus and normal oral mucosa

Publication at Faculty of Medicine in Hradec Králové |
2015

Abstract

Oral lichen planus (OLP) is potentially malignant disorder. Our objectives were to determine the prevalence of human papillomavirus (HPV) infection in patients with OLP in comparison with healthy oral mucosa and to compare the prevalence of HPV between red (erosive) and white (no-erosive) form of OLP.

Materials and methods: Forty-five OLP patients (73.3% women and 26.7% men) and 24 healthy individuals (79.2% women 20.8% men) were examined for presence of HPV. The positivity of HPV between red form (29 patients) and white form (16 patients) was compared.

HPV DNA was found in 53.3% of patients with OLP and in 50% in the control group. There was no statistically significant difference between HPV prevalence in control group and OLP group (p=0.79).

HPV positive were 16 (55.2%) patients from red group and 8 patients from white groups (50%) (p=0.74). No difference was observed between the healthy mucosa and OLP and between erosive and non-erosive forms.