Abstract
Mulberry (Morus L., Moraceae) is cultivated in China, Japan and Korea, and its leaves have been used for a long time to feed silkworms (Bombyx mori L.). Its leaves, twigs, roots (bark) and fruits are widely used in the traditional Chinese medicine.
The biologically active constituents of mulberry contained flavonoids, alkaloids, steroids, coumarins, with the significant hypoglycemic, hypolipidemic, anti-hypertension, anti-oxidation, anti-inflammatory, anti-bacterial, anti-tumor and immunomodulatory activities. Multi-herbal traditional medicine Samjunghwan, comprising including from mulberry fruits, is clinically used as anti-aging agents for neurodegenerative diseases and to promote longevity.
Neuroprotective effects of mulberry are confirmed by numerous studies conducted lately.