Publication at Faculty of Medicine in Pilsen |
2015
Abstract
Arterial hypertension and obstructive sleep apnea (OSA) occure often together; OSA represents a disorder of sleeping associated with snoring and hypopnoic or apnoic pauses taking of 10 s. Sleep apnea results in hypoxemia which stimulates sympathetic nervous activity and then heart rate and blood pressure (BP) increase.
However continuous positive airway pressure treatment is a gold standard therapy of OSA, BP reduction is small in patients with arterial hypertension, which significantly depends on night treatment compliance and on basal BP level. Hypertension should be still treated by drugs reducing sympathetic nervous activity in patients with OSA.