Abstract
Objective: The aim of the study was to determine whether there is a correlation between changes in visual fields, thickness of retinal ganglion cells and their axons in hypertensive and normotensive glaucoma and whether these findings differ in both diagnostic groups. Patients and methods of examination: A total of 100 eyes of 50 people, of whom 30 were women (25-82 years) and 20 men (21-81 years) were included in the study.
The first group included 26 patients with hypertensive glaucoma (HTG) (14 women and 12 men). The second group included 24 patients with normotensive glaucoma (NTG) (16 women and 8 men).
All patients were subject to the assessment of average thickness of the ganglion cell complex (GCC) by SD-OCT RTvue -100, retinal nerve fibre layer thickness by GDx (parameter NFI) and the visual field by the fast threshold program of Medmont M 700 device. Results: Correlation between studied parameters (GCC, NFI and visual field) was evaluated by correlation coefficients.
For the HTG group, there was moderately strong correlation between visual field changes (pattern defect -PD) and GCC (r = -0.5). There was also moderately strong correlation between GCC and NFI (r = -0.64) and between NFI and PD (r = 0.67).
Very weak correlation was found between GCC and the overall defect (OD) (r = 0.1). The above correlations were significant at the p = 0.05 significance level.
For the NTG group, there was moderately strong correlation between visual field changes (PD) and GCC (r = -0.42). There was also moderately strong correlation between GCC and NFI (r = -0.45) and between NFI and PD (r = 0.36).
Very [SYLWAN., 159(6)]. ISI Indexed 82 weak correlation was found between GCC and OD (r = -0.24).
The above correlations were significant at the p = 0.05 significance level. Conclusion: Examination of GCC and NFI showed moderately strong correlation for both NTG and HTG patients.
As we expected, the correlation was not identical between the two diagnostic groups.