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Samuels, M., H., Kolobova, I.,K., Smeraglio, A., S., Peters, D., Janowsky, J., S., Schuff, K., G.: The Effects of Levothyroxine Replacement of Suppressive Therapy on Health Status, Mood, and Cognition

Publication at First Faculty of Medicine |
2015

Abstract

The aim of the study was to determine whether women receiving TSH-suppressive L-T4 doses have decrements in health status, mood, or cognitive function. Women receiving TSH-suppressive doses of L-T4 do not have central nervous system dysfunction due to exogenous subclinical thyrotoxicosis, but TSH-suppressed and L-T4-replaced women have slight decrements in health status and mood that may be related to self-knowledge of the presence of a thyroid condition or other uncharacterized factors.

These mood alterations do not impair cognitive function.