Publication at Faculty of Medicine in Pilsen |
2016
Abstract
Psoriasis is a common, chronic and inflammatory disease of the skin, which has been associated with depression in cross-sectional studies with limited adjustment for confounders. In this prospective cohort study, we investigated the risk of incident depression among individuals with psoriasis and psoriatic arthritis (PsA).
We found an increased risk of depression in US women with psoriasis compared with those without psoriasis. This risk was higher in those who reported concomitant PsA.
Future studies are needed to confirm these findings in other populations and to identify pathophysiological mechanisms linking psoriasis to depression.