Charles Explorer logo
🇬🇧

Cholesterol metabolism in patients with type 2 diabetes

Publication at First Faculty of Medicine |
2016

Abstract

Diabetic dyslipidemia is a complex disorder associated with changes in lipid metabolism, which must be considered during care of the diabetic patient. Type 2 diabetes mellitus is a disease associated with a number of macrovascular and microvaskular complications and it is necessary to treat the patient with regard to the possibility of developing these disorders.

Prevention of cardiovascular complications is one of the most important factors of diabetes care, because cardiovascular diseases are among the leading causes of morbidity and mortality in patients with diabetes mellitus. The risk of developing atherosclerotic changes is significantly higher in diabetics in comparison with people without diabetes, which is mostly due to the differences in the plasma lipid metabolism and development of typical diabetic dyslipidemia with high atherogenic potentiak.

Treatment of diabetic dysluipidemia as well as prevention of cardiovascular events is based on adherence to lifestyle changes, that have a positive effect on diabetes itself, and a suitable pharmacotherapy selected to achieve terget plasma lipoprotein levels while affecting their quality.