Visual mismatch negativity (vMMN): A review and meta-analysis of studies in psychiatric and neurological disorders
Abstract
The aim of review and meta-analysis is to present findings from clinically-based studies of the visual mismatch negativity (vMMN) (an event-related potential component), to discuss its potential impact and application, to raise awareness of this measure and to improve our understanding of disease upon fundamental aspects of visual information processing. We discuss the physiological and theoretical basis of vMMN and review thirty-three studies from the emerging field of its clinical applications, presenting a meta-analysis of findings in schizophrenia, mood disorders, substance abuse, neurodegenerative disorders, developmental disorders, deafness, panic disorder and hypertension.
Furthermore, we include reports on aging and maturation as they bear upon many clinically relevant conditions. Surveying the literature we found that vMMN is altered in several clinical populations which is in line with aMMN findings.