Abstract
The goal of treatment of laryngeal carcinoma is to remove the tumor and prevent recurrence while maintaining laryngeal function. Early-stage laryngeal carcinomas (stage I-II) are treated with either definitive radiation or surgery that preserves laryngeal function.
Randomised trials helped establish the basis of larynx preservation approaches 1st and 2nd generation using radiation and chemotherapy in locoregionally advanced diseases (stage III-IV). Larynx preservation protocols provide equivalent tumor control to surgery, while allowing a substantial number of patients to avoid the mutilating sequel of surgical treatment.