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Immune thrombocytopenia: guide attending physicians: pathophysiology, diagnosis, therapy

Publication at Third Faculty of Medicine |
2015

Abstract

Thrombocytopenia is among the dreaded hematological disorders. With the decline in the number of platelets increases the risk of bleeding - petechiae, hematomas, metrorrhagia, gastrointestinal bleeding, but also fatal subarachnoid, or intracerebral hemorrhage intraretinálního.

Treatment options immune thrombocytopenia in the past 15 years sharply changed, except that now the traditional corticosteroids and conventional immunosuppressives, steroids sparing immunosuppressants (mycophenolate mofetil), androgens, anti-neoplastic drugs is currently dispzici immunoglobulin therapy and biological preparations (agonists thrombopoietin receptor, rituximab). The book clearly introduces physicians with clinically significant type of thrombocytopenia, focuses on immune thrombocytopenia, and its comprehensive and modern pharmacological and nonpharmacological therapy.