Abstract
Human papillomavirus (HPV) infection can cause cervical, vaginal, vulvar, penile, anal, and oropharynx cancers and genitals warts, too. These diseases are preventable thanks to HPV vaccination.
There is the new nine valent vaccine (HPV 6/11/16/18/31/33/45/52/58) available on the market. It provides high and consistent protection against infections and diseases related to the genotypes included in the vaccine.
The nine valent HPV vaccine shows a significantly increased impact compared to the quadrivalent vaccine (HPV 6/11/16/18) and it covers around 90 % of cervical cancers in women and 80-95 % of other HPV associated anogenital cancers in both men and women. The addition of HPV 31/33/45/52/58 increases the benefit of the vaccine by up to 20 % for invasive cervical cancers and up to 35 % for cervical precanceroses.
The efficacy against lesions related to HPV 31/33/45/52/58 reaches 97 %. The vaccination with new HPV vaccine will definitely affect cervical cancer screening programs in the future.