Publication at Faculty of Medicine in Pilsen |
2016
Abstract
Hidradenitis suppurativa (HS) is a chronic-relapsing, debilitating inflammatory disease affecting apocrine gland-bearing skin.[1] It is clinically characterized by recurrent, painful, deep-seated nodules commonly ending in abscesses and sinus tracts with suppuration and hypertrophic scarring, and is estimated to affect 1% of the population.[1] Treatment depends on the stage and severity of the disease, ranging from topical and systemic antibiotics for early and benign disease to immunosuppressive agents such as tumour necrosis factor-α blockers for more severe cases; for advanced and recalcitrant lesions, complete removal by surgical excision is regarded as the most effective procedure.