Paper deals with the immunity not only as an important part of reactivity of the organism, but also as a key pathogenetic factor. This is because of its links with neuroendocrine functions and joint mediator systems.
Immunity is therefore an important factor in psycho-neuro-endocrine relations both in health and also particularly in stress diseases. In the interdisciplinary psycho-neuro-immunology (PNI) the issue of immunity plays a decisive role.