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Porokeratoses

Publication at First Faculty of Medicine |
2016

Abstract

Porokeratoses represent a heterogeneous group of diseases which have in common the same histopathologic feature - the presence of cornoid lamela. Currently, there are seven the most frequent clinical variants.

The etiology of porokeratoses has not been fully elucidated yet. Combination of genetic predisposition and enviromental factors are playing role in the occurence of porokeratosis.

Guidelines for the treatment of porokeratosis have not been drawn up yet as the efficacy of the individual drugs or their combinations have been reported only in individual cases or small case series and controlled clinical studies are lacking. The authors give an overview of the current knowledge on porokeratosis.