Safety and Feasibility of Laparoscopic Nephrectomy for Big Tumors (>= 10 cm): A Retrospective Multicentric Study
Abstrakt
One hundred sixteen patients who had a laparoscopic nephrectomy for big tumors were included. Conversion to open surgery was necessary in 20.7%.
Hemorrhage occurred in 16.4%, resulting in open conversion in 62.5%. Intraoperative complications, age, and blood loss were predictive factors of conversion to open surgery.
Laparoscopic nephrectomy for tumors > 10 cm can be performed safely with comparable results to open surgery. Objective: Evaluate the feasibility of laparoscopic nephrectomy for big tumors.
Material and Methods: Data from 116 patients were retrospectively collected from 16 tertiary centres. Clinical and operative parameters, tumor characteristics, pre- and postoperative parameters, and renal function before and after surgery were analyzed.
Results: Mean age and body mass index were 61 years and 27.8 kg/m(2), respectively. Males represented 63.8% of patients, and 54.4% presented symptoms at diagnosis.
Median tumor size was 11 cm, and 75% of the cases were performed by expert surgeons. Median operative time and blood loss were 180 minutes and 200 mL respectively.
Conversion to open surgery was necessary in 20.7% of cases. Intraoperative complications related to massive hemorrhage occurred in 16.4% of patients, resulting in open conversion in 62.5%.
Major postoperative complications occurred in only 10 patients (8.6%). In univariate analysis, intraoperative complications, age, and blood loss were predictive factors of conversion to open surgery.
Positive surgical margins occurred in 6 patients (5.2%). None of them presented a local recurrence.
Predictive factors of recurrence or progression were lymph node invasion, metastases, and Furhman grade. Conclusion: Laparoscopic nephrectomy for tumors > 10 cm can be performed safely.
Complication rate and positive surgical margins are similar to open surgery. In experienced hands, the benefit of a mini invasive surgery remains evident.