Publication at Faculty of Science |
2015
Abstract
Oxorhenium(V) complexes composed of rhenium isotopes and suitable ligands gain increased interest in radiopharmaceutical medicine. Selected rhenium complexes with 1,2,3-trihydroxybenzene as ligand were prepared by a reaction of rhenium(+V) precursor (tetrabutylammonium tetrachlorooxo-rhenate) with twofold molar excess of ligand in acetonitrile.
The structure of formed complexes and their degradation products were obtained by mass spectrometry with electrospray ionization and else verified with nuclear magnetic resonance and infrared spectroscopy. The kinetics of reactions occurring in course of complex formation and subsequent degradation were followed by electrospray mass spectrometry and UV/VIS spectrometry.