Publication at First Faculty of Medicine |
2016
Abstract
Alpha1-antitrypsin deficiency, the most common genetic disorder seen in adults, is associated - in its severe form - with a high risk of pulmonary emphysema development. It is characterized by rapid decrease of pulmonary functions, often making the sufferers lung transplant candidates.
It the last years, it has been shown that regular administration of α1-antitrypsin slows down the destruction of lung tissue, thus likely modifying the course and prognosis of the illness.