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Complete nucleotide sequences of two VIM-1-encoding plasmids from Klebsiella pneumoniae and Leclercia adecarboxylata isolates of Czech origin

Publication at Faculty of Medicine in Pilsen |
2017

Abstract

Two MDR plasmids, carrying the VIM-1-encoding integron In110, were characterized. Plasmid pLec-476cz (311758-bp), from a Leclercia adecarboxylata, consisted of an IncHI1 backbone, a MDR region, and two accessory elements.

Plasmid pKpn-431cz (142876-bp), from a ST323 Klebsiella pneumoniae, comprised IncFIIY-derived and pKPN3-like sequences, and a mosaic region. A 40400-bp sequence of pKpn-431cz was identical to the MDR region of pLec-476cz, indicating the en bloc acquisition of the VIM-1-encoding region from one plasmid by the other.