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Rational use of psychotropic drugs in oncology - selected indications, interactions, tips for practice

Publication at First Faculty of Medicine |
2017

Abstract

Indications psychotropic drugs in oncology include also chemotherapyinduced neuropathy, delirium, nausea, emesis and affect appetite. Psychotropic drugs are often used "off label" and should be used in patients to attention.

Levels of some of psychotropic drugs may be affected by a number of concomitantly administered drugs due to pharmacokinetic drug interactions. Dexamethasone, phenytoin, and carbamazepine are often the comedication with the abovementioned indications, among the important enzyme inducers and may reduce the effect of psychotropic drugs.

Combinations of psychotropics potentially increased risk of pharmacodynamic drug interactions.