Functional split between social and spatial memory on a TGF 344-19 rat model of Alzheimer's disease

Abstract

TgF 344-19 animal model shows that its spatial orientation is literally devastated by AD at the age of 18 months. However, the social memory system seems functionally unaffected at the same age.

This finding shows a different progression of functional deterioration across two memory systems that seems of a particular interest given they share the same anatomical structure, hippocampus.

Keywords

• Memory
• Alzheimer Disease
• social memory
• spatial memory