Core-shell fibers based on the combination of soluble and insoluble types of hyaluronan were successfully created using wet-spinning method. High swelling of the fibers in synergy with tight textile structures were employed to ensure release of the dissolved fiber core through local cracks in the fiber shell.
Thanks to the biocompatibility and resorbability of hyaluronan, the braided or knitted textile structures made from these fibers have a potential to be employed as a drug carrier in medical applications.