Charles Explorer logo
🇬🇧

Histology of osteochondral defects healing

Publication

Abstract

Articular cartilage has a very limited potential for regeneration actuated after injury or disease. Healing of large osteochondral defects is typically accompanied by ingrowth of fibrous tissue and usually progresses to symptomatic degeneration of the joint.

Our aim was to evaluate the effects triggered by two scaffolds in a model using healing condylar cartilage on the surface of rabbit right femur. Characteristics of newly formed tissues were obtained through previously described standard histological techniques and differentiation of hyaline cartilage was traced